![]() your blood test results suggest poor kidney function (value of serum creatinine is 1.5 mg/dL (133 micromole/L) or greater).two or more of the following apply to you:.you have severely reduced kidney function.The recommended dose is one tablet of Eliquis 2.5 mg twice a day if: The recommended dose is one tablet of Eliquis 5 mg twice a day. To prevent a blood clot from forming in the heart in patients with an irregular heart beat and at least one additional risk factor. Take Eliquis as recommended for the following: medicines to treat tuberculosis or other infections (e.g., rifampicin).St John’s Wort (a herbal supplement used for depression).medicines to prevent epilepsy or seizures (e.g., phenytoin, etc.).The following medicines may reduce the ability of Eliquis to help prevent blood clots from forming: antidepressant medicines called selective serotonin re-uptake inhibitors or serotonin norepinephrine re-uptake inhibitors.medicines for high blood pressure or heart problems (e.g., diltiazem).Especially, if you are older than 75 years and are taking acetylsalicylic acid, you may have an increased chance of bleeding anti-inflammatory or pain medicines (e.g., acetylsalicylic acid or naproxen).other medicines that are used to reduce blood clotting (e.g., enoxaparin, etc.).some antiviral medicines for HIV / AIDS (e.g., ritonavir).some medicines for fungal infections (e.g., ketoconazole, etc.).The following medicines may increase the effects of Eliquis and increase the chance for unwanted bleeding: Your doctor will decide, if you should be treated with Eliquis when taking these medicines and how closely you should be monitored. Some medicines may increase the effects of Eliquis and some may decrease its effects. Tell your doctor, pharmacist or nurse if you are taking, have recently taken or might take any other medicines. If you are not sure whether a procedure may cause bleeding ask your doctor. If you need to have surgery or a procedure which may cause bleeding, your doctor might ask you to temporarily stop taking this medicine for a short while. if you know that you have a disease called antiphospholipid syndrome (a disorder of the immune system that causes an increased risk of blood clots), tell your doctor who will decide if the treatment may need to be changed.if your doctor determines that your blood pressure is unstable or another treatment or surgical procedure to remove the blood clot from your lungs is planned.This medicine will be used with caution in patients with signs of altered liver function.a liver problem or a history of liver problems.a severe kidney disease or if you are on dialysis.very high blood pressure, not controlled by medical treatment.bleeding disorders, including conditions resulting in reduced platelet activity.an increased risk of bleeding, such as:.Talk to your doctor, pharmacist or nurse before you take this medicine if you have any of the following: ![]()
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